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Forum | Internal Medicine Board Review Questions | Knowmedge 2024-10-24T10:35:30+00:00 http://knowmedge.com/forum/feed.php?f=22&t=8219 2024-10-24T10:35:30+00:00 2024-10-24T10:35:30+00:00 http://knowmedge.com/forum/viewtopic.php?t=8219&p=22242#p22242 <![CDATA[CAR-T Cell Detection ISH Probes]]>
Toxicity Assessment of CAR-T Cells

"On-target/off-tumor" toxicity was an expected side effect of CAR T therapy from the outset. In Situ Hybridization (ISH) is a great method that can be utilized to identify novel CAR-T cell targets and subsequently qualify monoclonal antibodies directed against those targets for immunohistochemistry. ISH can be used to predict CAR-T cell target organ toxicity in preclinical models.

Disrtribution Assessment of CAR-T Cells

Statistics: Posted by hannahcole — Thu Oct 24, 2024 10:35 am

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