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tPA Therapy: Contraindications

Pharmacology/CV
BbIiGSSS tPAA ("Bigs tPA")

BP > 185/110
Bleeding of GI or urinary tract in past 21 days
Intracranial hemorrhage previously
Infarct of myocardium recently
Glucose Blood < 50 or > 400 mg/dL
Surgery (major) in past 14 days
Stroke in last 3 months
Seizures at the onset of stroke

trauma of head last 3 months
Platelet count < 100,000/mm3
Age < 18
Anticoagulation INR > 1.7 or prolonged PTT
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