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Hemoglobin and Myoglobin: Binding Strengths, Sites

Physiology/CV
ABC of glycosylated Hb (Hb1c)
Glucose binds to Amino terminal of Beta Chain.

HbF binds Forcefully
HbF binds oxygen more forcefully than HbA, so Oxy-Hb dissociation curve shifts to left.

Stored blood is SOS
Stored blood Hb binds to Oxygen Strongly because of decrease in 2,3 BPG.

2,3 BPG binding site is BBC
BPG binds to Beta Chain of Hb.

Myoglobin binding strength is MOM
Myoglobin binds Oxygen More strongly than Hb.
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