A quick search will reveal . Spirit Airlines is a popular option for budget travel, while Delta offers more amenities. This route is also serviced by Frontier Airlines, which offers competitive rates. If your question is about which airlines operate flights from Orlando MCO to Las Vegas LAS, be sure to also consider the flight duration and layover options. The majority of airlines provide direct flights that last approximately five hours. Due to the high traffic on this route, several departures are planned each day. Search for seasonal deals or flight packages. Make sure to include baggage and seat selection fees in your calculations. Selecting the appropriate airline can enhance your trip's smoothness and enjoyment.