The debate over: Which is better Arimistane or Nolvadex estrogen blocker usually ends with context. Arimistane acted as a milder support option that some athletes preferred during lighter cycles. Nolvadex, being a prescription SERM, showed stronger results for recovery in heavier stacks. Experienced users advised that choice depends on the cycle’s intensity and health monitoring, as both serve different levels of support rather than being direct replacements.